Ladenburg Thalmann & Co. Inc.
                               590 Madison Avenue
                              New York, N.Y. 10022


August 9, 2005

Securities and Exchange Commission
Division of Corporate Finance
100 F. Street, N.E.
Washington, D.C.  20549

     Re:  Electro-Optical Sciences, Inc. (the "Company") Registration Statement
          on Form S- 1 (Reg. No. 333-125517)
          ----------------------------------

Ladies and Gentlemen:

     In accordance with Rule 461 of the General Rules and Regulations under the
Securities Act of 1933, as amended (the "Act"), we hereby join with the Company
to request that the effective date for the Registration Statement referred to
above be accelerated to 4:30 p.m., (New York time) on August 9, 2005 or as soon
as practicable thereafter.

     In connection with Rule 460 of the Act, please be advised that, during the
period from July 15, 2005 to August 5, 2005, we have effected the following
distribution of copies of the Preliminary Prospectus dated July 15, 2005:

     Number of prospectuses distributed to institutions         1975
     Number of prospectuses distributed to individuals          7150
     Number of prospectuses distributed to underwriters          600
                                                         -----------
     Total                                                      9125

     Also in connection with Rule 460 of the Act, please be advised that, during
the period from August 8, 2005 to the date of this letter, we have effected the
following distribution of copies of a revised Preliminary Prospectus dated
August 8, 2005:

     Number of prospectuses distributed to institutions         1200
     Number of prospectuses distributed to individuals          2050
     Number of prospectuses distributed to underwriters          600
                                                          ----------
     Total                                                      3250

     The undersigned has and will, and each participating underwriter and dealer
has advised the undersigned that it has and will, comply with the provisions of
SEC Release No. 33-4968 of the Act and Rule 15c2-8 of the Securities Exchange
Act of 1934, as amended in connection with the above-referenced issue.



Very truly yours,

LADENBURG THALMANN & CO. INC.
STANFORD GROUP COMPANY

By:  LADENBURG THALMANN & CO. INC.

By: /s/ Salvatore Giardina
    ------------------------------
Name:   Salvatore Giardina
Title:  Executive Vice President & Chief Financial Officer








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